Over time, the pathogen developed resistance to the β-lactamase, which led to the introduction of methicillin, a penicillin-like cell-division-suppressing antibiotic, as a treatment alternative.

Zai Lab and Pfizer have entered a strategic collaboration to commercialise XACDURO (sulbactam-durlobactam), a new ...

† VIMs are made up of 266 amino acid residues with the exception of VIM-7 (265 residues) and VIM-18 (262 residues). VIM-21, -22 and -27 have been assigned in the Lahey Clinic [201], but there ...

Cefdinir is stable in the presence of some, but not all, β-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins are susceptible to cefdinir. Treatment ...

8). Figure 1: A sequence alignment of amino-acid residues near the H-9 (α9) and H-10 (α10) helix of class C β-lactamases with extended substrate spectrum.

This combination medication contains semisynthetic antibiotic amoxicillin and β-lactamase inhibitor, prescribed for lower respiratory infections, otitis media, sinusitis, urinary tract infections ...