ATR and ATM kinases are key factors for the surveillance of DNA replication, and prevent chromosome breakage in dividing cells. However, during repair processes, chromosome fragments can be ...
replicated chromosomes are held together by linkages (cohesion) until they are separated by the mitotic spindle apparatus. Our lab showed that an analogous cohesion process occurs in bacteria, in ...
These predictions were as follows: According to the semiconservative model, after one ... double-stranded DNA unwinding at a single spot on the chromosome known as the replication origin.