Screening prospectively for HLA-B*5701 — and avoiding abacavir use in those who test positive — reduces the incidence of hypersensitivity reaction to this NRTI. Abacavir is an attractive drug ...

The association of abacavir hypersensitivity syndrome with HLA-B*5701 is one of the strongest associations ever described between an immunogenetic marker and 'disease'. HLA Screening ...