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Acromegaly: A disease that causes adults to grow uncontrollably
Patients with acromegaly make too much growth hormone, which causes them to grow disproportionately large bones, organs and ...
Crinetics Announces FDA Acceptance of New Drug Application for Paltusotine for Adult Patients with Acromegaly
Paltusotine was granted Orphan Drug Designation for the treatment of acromegaly by the FDA in July 2020. This designation is provided to drugs defined as being intended for the safe and effective ...
Nature5y
High IGF-I levels imply active acromegaly even when GH levels are 'normal'
with noncured acromegaly. Serum IGF-I and GH levels were measured by validated assays. In total, 81 patients had active disease (IGF-I and GH both high), 68 patients had biochemically controlled ...