Biochemical control of acromegaly in noncured patients is usually defined as serum growth hormone (GH) levels <2.0 µg/l, plus normal-for-age serum levels of insulin-like growth factor I (IGF-I).

Colleen, from Virginia in the United States, suffers from a rare genetic condition called acromegaly or gigantism. The gene caused Charles Byrne, born in 1761 near Cookstown and known as the ...