Many people think that a cup of coffee will wake them up and make them have more energy - but as it turns out, having one too ...

The administration of a pharmaceutical composition comprising an A3 adenosine (A3AR) agonist has been found to alleviate the symptoms of neuropathic pain regardless of the cause or location, or ...

We have been exploring the potential of the neuromodulator, adenosine, to reduce excessive dopamine signaling that contributes to the development and persistence of psychostimulant abuse. Dopamine’s ...

Exploration of adenosine mechanism revealed adenosine receptors as a potentially useful target of therapy in RA.

Consider adenosine A 2A receptor antagonists, for example, which are being evaluated as an adjuvant therapy to L-dopa or D 2 receptor agonists for Parkinson's disease, based on the evidence of ...

Exploration of adenosine mechanism revealed adenosine receptors as a potentially useful target of therapy in RA. Principal signaling pathways activated by adenosine receptors. AC: Adenylate ...

Caffeine's stimulating effects can paradoxically lead to sleepiness due to tolerance, adenosine receptor changes, and individual metabolic differences.

Piclidenoson, an orally administered drug, has demonstrated a safety and efficacy profile in a Phase III trial for psoriasis ...

Sleep is essential for health. According to one estimate, roughly 56% of people in the United States experience sleep issues, ...

Pumpkin seeds are a bonafide superfood and certified stress reliever. Pumpkin seeds and pepitas (the seeds without the shells ...

This is because the body develops a tolerance to caffeine. Caffeine binds to a receptor in the brain used by adenosine. The binding of caffeine to these receptors causes the body to delay the onset of ...