Importantly, SIRT1 and USP7 regulate the activity ... In addition to PI3P lipids, activation of AKT/PKB requires phosphorylation on a specific residue by the phosphoinositide-dependent kinase ...

But the activity of AKT itself is also switched on through phosphorylation by other protein kinases. In the early 2000s, scientists had established that the AKT protein is activated by two separate ...

Phosphorylation is the enzymatic process through which a phosphate group is added via an ester bond, generally by a kinase, to either a small molecule or a protein. Protein phosphorylation is ...

Coagulation factor X performs its' function through increasing the phosphorylation and activation of ERK1/2 (ERK can also enhance the angiogenesis of the tumour) and AKT in macrophages. After that, ...

310 (2023) 116418]. Sargentodoxa cuneata and Patrinia villosa extract inhibits LPS-induced inflammation by shifting macrophages polarization through FAK/PI3K/Akt pathway regulation and glucose ...