RA: What is Alkaptonuria and how does it affect patients? OT: Alkaptonuria (AKU) is a rare genetic disease that causes early-onset, severe osteoarthritis. It was discovered more than 100 years ago ...

A single-gene disorder identified by Archibald Garrod that is characterized by dark urine. Garrod first coined the term "inborn error in metabolism" to describe this ...