A survey of single–amino acid substitutions found that substitutions closer to the active site give larger improvements in enantioselectivity or diastereoselectivity than substitutions further ...
The final DAPDH variant contains five amino acid substitutions and achieves the goal of being useful for synthetic applications. It shows good activity and high enantioselectivity and now accepts ...
In a paper published in Polymer Science & Technology, an international team of scientists explores how modifying side-chain ...