"The individual proteins are always changing in response ... their organization and how that relates to the overall structure of the amyloid protein. Aβ42 is constantly changing, and step one ...

A new study represents a significant step forward in scientists' understanding of Alzheimer's disease. A team of investigators has examined the role of two proteins found in the brain and suggest the ...

A recent study in Nature Neuroscience provides new insights into how amyloid-beta and tau proteins, which accumulate in the ...

This manuscript provides fundamental studies to help us better understand the effects of mutations in the presenilin-1 (PSEN1) gene on proteolytic processing of the amyloid precursor protein (APP).

Certain proteins can adopt multiple distinct amyloid shapes ... polyphosphate will nestle into exactly the same pocket in the structure of brain-derived fibrils that the real mystery density ...

Researchers have uncovered how certain genetic mutations lead to unique spherical amyloid plaques in inherited forms of ...