The technology – called Antibody Transport Vehicle (ATV): Amyloid beta – can be used to help amyloid-targeting drugs cross the blood brain barrier (BBB) more effectively, say the partners.
The cascade component of the hypothesis captures the idea that the production of Aβ not only leads to amyloid plaques, but also has other downstream effects including hyperphosphorylation of tau ...
The research was published in the FEBS Journal and means the team can now search for molecules to make the enzyme work better to lower the production of the amyloid beta. “We are in a great ...
Targeting pyroglutamate amyloid beta, Aliada's main antibody is investigational and helps to explain the production of amyloid plaques, a hallmark of Alzheimer's disease. Under Phase 1 clinical ...