[6,7,8,9,10,11] Published reports that evaluated topiramate-associated hyperchloremic, normal anion-gap, metabolic acidosis were identified via a MEDLINE search (1966-May 2007) and included six ...

Use of the Naranjo et al. [12] adverse drug reaction probability scale indicated a probable relationship between hyperchloremic, normal anion-gap, metabolic acidosis and topiramate. This adverse ...

Depending on the cause of metabolic acidosis, an imbalance in positively vs. negatively charged electrolytes may also exist.

Despite an important loss of potassium, initial serum potassium levels appear normal or increased due to the extracellular migration of potassium in response to acidosis. However, during treatment ...