These findings in the human are at the basis of our proposed structure-function model in which the antigen binding features of the germline template antibody are dictated by the somatically ...

As part of an international collaboration, Fred Hutch scientists provided structural information that helped reveal how two ...

Antibodies are Y-shaped proteins that reach out to their targets with the tips of each arm. If the antibody interacts with a ...

assembling these proteins into cage structures allows its scientists to fine-tune the antibody’s properties without having to change the structure of the antibody itself. For example ...