As part of this month's special focus on apoptosis, two researchers in the field discuss their role in the development of therapeutic strategies to target apoptosis. David Huang, MBBS, MRCP (UK ...

Figure 1: Etoposide-induced apoptosis in EL4 cells analyzed using flow cytometry and DNA gel electrophoresis. Figure 3: MR images of a tumor in a drug-treated mouse following injection of C 2 ...

Abstract: We previously observed that p53-mutated human epithelial tumor A431 cells underwent apoptosis after ultraviolet C (UVC) irradiation through the caspases-8 and -3 pathway. Fas/FasL is known ...

Objectives Induction of apoptosis is often associated with an oxidative stress response. N-(4-[18F]fluorobenzoyl)cystine (18F-FBC), a potential substrate of the cystine-glutamate exchanger (xCT) which ...

Aims: We hypothesised that important neuropathological abnormalities of the large bowel are present, that these are not confined to the interstitial cells of Cajal and ganglion cells, and that the ...

Objectives The goal of this study is utilization of apoptosis imaging with F-18 labeled rh-his10-annexin V to early assess the response after paclitaxel treatment in nude mice bearing A549 tumor and ...