Over four hundred people, 80% of them being children under 14 years old, will be diagnosed with B-cell Acute Lymphoblastic (B ...

引言肿瘤免疫微环境对癌症的发生、预后及治疗的贡献已广为认可，尤其是在固有免疫因素和T细胞亚群的研究方面。然而，尽管有证据表明肿瘤浸润B细胞在多种癌症中占据显著比例，甚至在某些情况下占所有肿瘤浸润淋巴细胞的40%，但肿瘤免疫微环境中B细胞的研究相对较少 ...

INT2104 has the potential to overcome ex vivo CAR therapy challenges with a single-dose, off-the-shelf, widely accessible therapy for the treatment of B cell malignancies enabled by Interius’s ...

【导读】铁是人体必需的生物矿物质。在这项研究中，团队描述了一个载铁癌症相关成纤维细胞的子集，称为FerroCAFs，它们利用铁诱导前列腺癌中的免疫抑制并预测不良的临床结果。2024年10月20日，上海交通大学医学院附属仁济医院朱鹤团队在期刊《Natu ...

Immunotherapy and precision medicine show promise in better fighting cancer. What else does the research tell us?

Researchers from Shanghai Institute of Biological Products Co. Ltd. published details on the development and preclinical characterization of novel CD20-targeting T cell-dependent bispecific Fab-FabCH3 ...

Breast cancer is the number one cancer among women: more than 2 million cases were diagnosed worldwide in 2022. It is also ...

奥希替尼是一种三代表皮生长因子（Epidermal Growth Factor Receptor, EGFR）酪氨酸激酶抑制剂（Tyrosine Kinase Inhibitor, TKI），目前是携带 EGFR ...

Patients with low-count chronic lymphocytic leukemia phenotype monoclonal B-cell lymphocytosis had a 1.86-fold greater risk ...

Endocrine Neoplasia Translational Research Center, Division of Endocrinology, Diabetes and Metabolism, Chaim Sheba Medical Center, and Tel Aviv University Faculty of Medicine, Ramat Gan, Israel This ...

Alicia Zhou, PhD, became CRI’s president effective August 26, and succeeded Jill O’Donnell-Tormey, PhD, who had led the Institute since 1993.

近日， Journal of Thoracic Oncology (中科院一区，影响因子21分 )在线刊登了高剂量伏美替尼治疗EGFR突变非小细胞肺癌（non-small cell lung cancer, ...