while osteoblastic bone formation is controlled by canonical Wnt signaling. Antiresorptive bisphosphonates remain the mainstay of treatment but recombinant parathyroid hormone is increasingly ...

RANKL/osteoprotegerin/RANK signaling regulates bone resorption and is essential for osteoclastogenesis, osteoclast activity and survival. Canonical Wnt signaling regulates bone formation and is ...