Lymphocyte activation occurs when lymphocytes (B cells ... Here the authors explore how sAg impacts CD4 and CD8 T cell subsets, leading to either expansion or excessive release of pro-inflammatory ...

"One of the most intriguing findings of the study is that the skin or epidermal cells known as keratinocytes play a key role in arming the T cells. Keratinocytes not only activate the CD8 + T-cell ...

Patients with melanoma brain metastases had better survival if they received radiotherapy (RT) followed by immunotherapy ...

A new study provides important insights into how T-cells, a type of immune cell, become activated. Researchers employed a technique called Bayesian metamodeling, which combines data from different ...

Their study, published in Oncogene, explores how increased methylmalonic acid impairs the activation and effector functions of CD8+ T cells, immune cells that play a vital role in fighting cancer.

Moreover, in people with MS and subclinical neuroinflammation, CD8 + T cells in the peripheral blood and cerebrospinal fluid expressed genes associated with increased activation, antigen ...

MDNA11 shows significant survival benefits in preclinical glioblastoma models, expanding CD8 + T and NK cells Bizaxofusp selectively targets human tumor cells and immune-suppressive cells, enhancing ...

Equillium Inc. (Nasdaq: EQ), a clinical-stage biotechnology company leveraging a deep understanding of immunobiology to ...

Results from a new animal study found that maternal exposure to e-cigarette residues, with or without nicotine, affected ...

A new study has found a surprising link between high levels of methylmalonic acid and the weakening of CD8+ T cells, shedding light on potential pathways through which aging may promote lung cancer ...