"One of the most intriguing findings of the study is that the skin or epidermal cells known as keratinocytes play a key role in arming the T cells. Keratinocytes not only activate the CD8 + T-cell ...

Their study, published in Oncogene, explores how increased methylmalonic acid impairs the activation and effector functions of CD8+ T cells, immune cells that play a vital role in fighting cancer.

Moreover, in people with MS and subclinical neuroinflammation, CD8 + T cells in the peripheral blood and cerebrospinal fluid expressed genes associated with increased activation, antigen ...

Memory CD8 + T cells are the mature version that has encountered an antigen before and create an immune response if it is reencountered. Lower levels of apoptosis were also seen in the CD4 + T cells ...

MDNA11 is a next-generation IL-2 superkine designed to selectively stimulate effector immune cells (CD8 + T cells and NK cells) by enhancing affinity for IL-2Rβ (CD122) while avoiding IL-2Rα (CD25), ...