The steady accumulation of knowledge about the multifarious roles of glial cells, in both healthy and diseased states, has greatly added to the complexity of our picture of the CNS. However ...

different glial cell types make myelin in a different manner. Schwann cells make myelin in the peripheral nervous system (PNS: nerves) and oligodendrocytes in the central nervous system (CNS ...

The Deneen Lab seeks to unlock the enigmatic biology surrounding glial cell development and function in the brain. Beginning with developmental gliogenesis, we identified the key transcriptional ...

The complexity of the central nervous system (CNS) and its pathologies necessitates an intricate understanding of the cellular and molecular mechanisms at play. Single-cell biology has emerged as a ...

2 The CNS is made up of neurons and glial cells, with the latter group—including astrocytes, oligodendrocytes, and microglia—exhibiting greater diversity and function than neurons. Once ...

These results suggest that inflamed CNS may have heightened responsiveness to IL-17A. To determine whether neonatal glial cells in culture also express IL-17RA at the protein level we labeled ...

Unlike other organs that have fat cells, neurons and other cells in the central nervous system (CNS ... a study investigating ...