Studying the evolution of cancer malignancy in space and time provides clues that are crucial for understanding how tumors develop, how they evade the immune system, and how they resist therapy ...

Researchers at the University of Cologne and the Centre (CRG) in Barcelona have discovered that cancer grows uniformly throughout its mass, rather than at the outer edges.

Cancer cells on the surface are thought to have natural advantages compared to cells deep within, which is why scientists have hypothesized tumors grow more in their periphery than in the core. A ...

Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...

The findings offer new insights into cancer evolution while challenging Peto's paradox -; a key concept in evolutionary biology. Peto's paradox suggests that larger animals, with their greater ...

In a new review, Arizona State University researchers, working with colleagues around the world, explore how established ...

Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists used state-of-the-art ...

Microbes profoundly impact evolution, shaping traits alongside genes. Holobiont biology highlights how hosts and microbes ...

On the wall of Dian Yang's office hangs a painting of a "Pandora's box of cancer" being opened with a molecular key. From ...

A multi-institutional team of researchers, led by Georgia Tech's Francesca Storici, has discovered a previously unknown role ...

Researchers at the University of Cologne develop three-dimensional mathematical model of prostate cancer. The model depicts various processes, including tumour growth, genetic evolution and tumour ...