The cell must also pass through a series of checkpoints that ensure conditions are favorable for division. In order to move from one phase of its life cycle to the next, a cell must pass through ...

Other proteins act to hold the cell at distinct points in the cycle (checkpoints) and are known as tumor suppressor genes. Apart from those with a clearly regulatory role, many proteins have ...

CHK1 is important for the activation of S, G2 checkpoints in response to DNA damage and replicative stress and is involved ... and concept for the project that CHK1 inhibition was therapeutically ...

A review discussing the therapeutic potentials of NK cell biology has been published in the journal Frontiers of Medicine. This exhaustion is influenced by immune checkpoint receptors, which are ...

This exhaustion is influenced by immune checkpoint receptors, which are inhibitory cell surface receptors that can suppress antitumor immunity. Notably, intracellular checkpoint molecules within ...

This exhaustion is influenced by immune checkpoint receptors, which are inhibitory cell surface receptors that can suppress antitumor immunity. Notably, intracellular checkpoint molecules within ...