Expression of the cell cycle inhibitor p15 INK4b is suppressed by the Myc oncoprotein and induced by transforming growth factor-β (TGF-β). The transcription factor Miz-1 activates the Ink4b ...

MYC is a transcription factor that plays relevant roles in cellular processes such as glycolysis, development, cell differentiation or proliferation. Recent research has associated the transcriptional ...

The simultaneous inhibition of the transcription factors Myc and JunB could represent a pioneering therapeutic option for the ...

作者 | 谢思燕1，郑忠信2，焦营营2，李珍2单位 | 1.桂林医学院第二附属医院检验科，2.南方医科大学南方医院血液科前言伯基特淋巴瘤(Burkit ...

Melanoma is a type of cancer that originates from melanocytes, the cells responsible for producing skin pigment, and is known ...

【第2集】BBC.The.Cell- 细胞 - 科普类型纪录片(1)（中） 译 BBC.The.Cell- 细胞 - 科普类型纪录片 - BBC.The.Cell- 细胞 - 科普类型纪录片(1)（中） ...

Thus, an emerging strategy for the treatment of those conditions is to inhibit cellular proliferation by targeting cell cycle regulation. Here we will review the current understanding of the ...

Proliferation index is an important prognostic factor in breast cancer. The Ki-67 protein is expressed in all phases of the cell cycle except G0 and serves as a good marker for proliferation. Studies ...

PCNSL relapse was histologically confirmed in October 2021, with expression of CD20, BCL2, BCL6, MUM1, and c-Myc ... T-cell therapy. The first question is whether the observed T-cell proliferation ...

15, 2024 — A team tests the protective effect of a fermented black garlic extract against inflammation and the progression of prostate cancer in a study conducted on human prostate cancer cell ...

The work presented will be of interest to cancer biologists and more broadly to those interested in NSCLC translational studies. Non-small cell lung cancer (NSCLC) is the most common subtype of lung ...