Clathrin-mediated endocytosis is a major endocytic route used by transferrin, growth-factor receptors and pathogenic viruses during infectious entry. Although clathrin-dependent uptake is the best ...

Clathrin triskelions, comprised of three clathrin heavy chains (CHC) and three tightly associated light chains (CLC), assemble into a polygonal lattice, which helps deform the overlying plasma ...

The cellular membrane controls the passage of substances in and out of the cell. Some larger cargo, such as membrane proteins ...

One key process in maintaining this equilibrium is endocytosis, the mechanism by which membrane components are internalised. Organisms have evolved various endocytic pathways, all relying on ...