It works by reducing acne-causing bacteria. Topical clindamycin works best when it’s combined with other acne treatments like ...

It may be used in combination with other acne treatments. Clindamycin is used to treat a wide variety of bacterial infections. Spironolactone is used to treat high blood pressure and heart failure.

Benzoyl peroxide has antibacterial activity. Topical antibiotics available for treating acne include clindamycin (1% gel, lotion, solution, or pledgets applied b.i.d.), erythromycin (2% gel ...