The crystal structure of a second G protein–coupled receptor sheds light on these key pharmaceutical targets. In contrast, β2AR and essentially all of the other GPCRs are present at very low ...
well ordered protein crystals in microgravity for highly medically relevant proteins that are difficult to crystallize in 1-g. From these crystals, molecular structures will be obtained and new drugs ...
Freed from the surrounding protein, however ... from which the hemozoin could be extracted. Revealing the structure of these natural crystals was crucial for medical applications, particularly ...
WNKs sense osmotic pressure by binding specific water molecules to the inactive dimeric configuration of WNK1 and WNK3, integrating signals with chloride inhibition as demonstrated by mutagenesis and ...