The most common method used to study protein structures is X-ray crystallography. With this method, solid crystals of purified protein are placed in an X-ray beam, and the pattern of deflected X ...

including in structure-based drug design. Drago began exploring a technique to pinpoint otherwise elusive hydrogens that ...

The use of X-ray crystallography to determine protein structure requires the production of well-ordered protein crystals that are of sufficient quality. Without high quality crystals of a protein, it ...

The crystal structure of a second G protein–coupled receptor sheds light on these key pharmaceutical targets. In contrast, β2AR and essentially all of the other GPCRs are present at very low ...

Prof. Leslie Leiserowitz first became intrigued by malaria when he was a young boy in South Africa. His father, who scouted ...

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called ...

Researchers at New York University have devised a mathematical approach to predict the structures of crystals—a critical step in developing many medicines and electronic devices—in a matter of ...

Wood exposed to space for approximately 10 months showed no change in weight and no erosion due to atomic oxygen. This ...

Space-grown crystals could lead to targeted cancer drugsResearchers used space-grown protein crystals to determine the ...

WNKs sense osmotic pressure by binding specific water molecules to the inactive dimeric configuration of WNK1 and WNK3, integrating signals with chloride inhibition as demonstrated by mutagenesis and ...