This study highlights the importance of proteins that are involved in the regulation of the actin cytoskeleton, revealing fundamental roles for HEM1 in both innate and adaptive immune cells.

The actin cytoskeleton provides force for dynamic cellular processes, such as motility, morphogenesis, cell division, endocytosis, and phagocytosis. The organization and dynamics of actin filaments ...

3D microscope image showing separation of actin isoforms in a cluster of cells. The uppermost layer (stained red) consists of gamma actin, whilst the base and edges display beta actin (green ...

We recently discovered that these structures are essential for the establishment of reticular adhesions. In our lab, we aim to elucidate the interplay of clathrin structures with the actin ...

That work showed that it does this by activating actin cytoskeleton, which provides structural support to cells, allowing ...

The story of the cell cycle is often told only through the perspective of the chromosomes as they replicate and then divide. This resource beautifully illustrates the role of the cytoskeleton in that ...

This release of actin may be important for allowing the ... to a deeper understanding of how cells assemble their microtubule ...

In regards to gonadotropes, it has been shown that migration of secretory granules and release of LH requires an intact cytoskeleton although the precise mechanisms that regulate actin reorganization ...