This folate-trapping mechanism causes the death of the MTHFD2-expressing cancer cells only. Moreover, targeting nuclear MTHFD2 interferes with its DNA damage repair functions (Fig. 1) in an ...
It also plays an important role in DNA synthesis and repair. What is the difference between folic acid and folate? Folic acid is a synthetic form of folate that is commonly found in supplements ...
These genetic changes can lead to a lack of folate, an essential nutrient that plays a crucial role in various body functions such as DNA synthesis and repair. Methylfolate supplements offer a ...