A team of scientists at the University of Illinois discovered naturally-occurring DNA-protein hybrid molecules last ...

双链核酸的序列特异性靶向是分子诊断和原位成像的重要组成部分。CRISPR相关蛋白（Cas）在crRNA的引导下，通过识别原间隔区相邻基序（PAM）来切割靶标核酸。然而，CRISPR-Cas系统对PAM的依赖性以及脱靶效应不仅限制了其靶标范围，且影响了 ...

But despite causing major diseases, these slightly mutated proteins can resemble their normal versions so closely that ...

The viruses that infect bacteria are the most abundant biological entities on the planet. For example, a recent simple study of 92 showerheads and 36 toothbrushes from American bathrooms found more ...

A new study describes the development of a biologic, a drug derived from natural biological systems, that targets a mutant cancer protein called HER2 (human epidermal growth factor receptor 2) without ...

190位诺贝尔化学奖得主中，有8位女性。分别是1911年的居里夫人（居里夫人另外还获得1903年的物理学奖）、1935年的Irène Joliot-Curie、1964年的Dorothy Crowfoot Hodgkin、2009年的Ada ...

Scientists at NYU have created a drug that targets cancer-causing HER2 mutations without harming healthy cells. This new ...

Consider the difference between the two letters “i” and “j.” You can recognize the difference, even with an unusual font or ...

Examining the advantages of saliva samples for genomics and microbiome researchers as a source of total nucleic acids.

For some proteins, a single mutation, or change in its DNA instructions, is all it takes to tip the balance between ...

Antibodies show promise as candidates for therapeutics as well as tools for advancing mechanistic studies of the HER family receptors.

Soft Condensed Matter and Biophysics, Department of Physics and Debye Institute, Utrecht University, Utrecht, The Netherlands ...