This study utilizes an elegant approach to examine valence encoding of the mesolimbic dopamine system. The findings are valuable, demonstrating differential responses of dopamine to the same taste ...
This pathway, an indirect connection to the ... which enters the striosomes from the cortex and the limbic system, influences dopamine levels in a way that can encourage or discourage action.
The findings suggest that the classical model of how the striatum controls movement needs to be modified to include the role of these newly identified pathways. The researchers now hope to test their ...
This supersensitivity might be the result of changes in receptor number and cellular distribution, or changes in the signalling pathways downstream of receptor activation. As enhanced D1 dopamine ...