The pharmacotherapy of schizophrenia is currently dominated by atypical antipsychotics that primarily target dopaminergic signalling ... modulate muscarinic receptors by targeting the ...

Scientists have recently discovered that caffeine may counteract some of alcohol’s effects on the brain’s reward system, ...

low doses of caffeine prevent the process of activation of the mesolimbic dopaminergic pathway by alcohol through a mechanism of action that involves specific receptors and alcohol’s metabolism ...

Destruction of the ascending dopaminergic pathway, blocking of dopamine receptors by drugs, inhibition of dopamine synthesis, or prevention of dopamine storage has been shown to induce akinesia on ...

In contrast to antipsychotics that work on dopaminergic and serotonergic receptors in the brain, the oral agent targets the M1 and M4 muscarinic receptors instead. The novel approach may help ...

Bromocriptine activates post-synaptic dopamine receptors. The dopaminergic neurons in the tuberoinfundibular process modulate the secretion of prolactin from the anterior pituitary by secreting a ...

The transplantation of astrocytes — a type of brain cell as common as neurons — may provide hope of treatments or cures of some neurodegenerative disorders.