A number of cell surface and nuclear receptors mediate their actions via dimerization. While this has been well established, the dimerization of G-protein coupled receptors (GPCRs) (that ...

Researchers in biology and medicine have long dreamed of controlling the activities of cells without, for example, having to ...

The human gut is home to helpful microbes, called the microbiota, who produce molecules known as metabolites. These ...

Septerna upped the size of its offering twice before pricing a stock sale that raised funds for its lead candidate, a ...

Septerna may be yet to disclose “any meaningful clinical data,” but the biotech clearly thinks there will be investor ...

A 2A R is a member of major drug targets G protein-coupled receptor (GPCR) superfamily, which engages the G protein and initiates cell signaling, influencing heart health, inflammation ...

The 2012 Nobel Prize for Chemistry has been awarded to Robert Lefkowitz and Brian Kobilka for groundbreaking discoveries that reveal the inner workings of G-protein-coupled receptors. Professor David ...

Septerna CEO Jeffrey Finer rang the opening bell on the Nasd | South San Francisco-based Septerna has scored with an upsized ...

Researchers from Osaka University have discovered that GPR31, found in certain immune cells in the human gut, plays a key ...

Endothelin is a peptide hormone known for its vasoconstrictive effects. Researchers at University of Tsukuba used ...

AHA 2024 Presentation Details (being held in Chicago, IL, Nov 16-18, 2024): Title: The tolerability, safety, pharmacokinetics, and pharmacodynamics of TX000045, a long-acting Fc-relaxin fusion protein ...