Recent structural data support the idea that GPCRs, despite their small size, are sophisticated allosteric machines with multiple signaling outputs. You have full access to this article via your ...

As the largest family of cell surface receptors, GPCRs account for over one-third of drug screening efforts. Inositol-1-phosphate (IP1) is a metabolite of Gq signaling and has been shown to be very ...

G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research. Diabetes results from ...

We also develop phototropin and cryptochrome-based optogenetic tools for regulating G protein signaling independent of GPCRs. These engineered tools allow the acquisition of dynamic molecular pictures ...

A 2A R is a member of major drug targets G protein-coupled receptor (GPCR) superfamily, which engages the G protein and ...

In this webinar brought to you by BPS Bioscience, Junguk Park and Vanda Lopes will discuss reporter cell line development and optimization in three functional categories: cytokine signaling (TSLP and ...

Let’s take a look at how differential signaling is different from single ended, and what that means for engineers and for users. Collectively, standards like TTL, CMOS, and LVTTL are known as ...

Agonists that extend formation of the platelet plug generally bind to G protein-coupled receptors on the platelet surface ... We have more recently shown that arrestin-2 regulates the function of PI3K ...

The G protein-coupled receptor (GPCR) specialist is asking investors to fund development of its lead hypoparathyroidism candidate through phase 2 before it shares initial data in humans.

More information: Kun-Yang Lin et al, Astrocytes control quiescent NSC reactivation via GPCR signaling–mediated F-actin ...

Why ASLAN Pharmaceuticals Shares Are Trading Lower By Over 38%? Here Are Other Stocks Moving In Wednesday's Mid-Day Session Avi Kapoor Obesity-Drugs Focused Stocks Tumble On Wednesday - What's ...