is a specialized form of basement membrane that has a major role in the maintenance of the glomerular filtration barrier. Like all basement membranes, it contains four main components: type IV ...

The US National Kidney Foundation defines an estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m 2 as evidence of chronic kidney disease. Decreased eGFR is associated with increased ...

Filtration is dependent on the unique structure of the capillary wall comprising layers of two key cells types, glomerular endothelial cells (GEnC) and podocytes, separated by a specialised basement ...