HIF innate immune activities are evident not only in phagocytic cells such as macrophages and neutrophils but also in dendritic cells, mast cells and epithelial cells with important host defence ...

In particular, macrophage immune cells depend on proteins that are activated by hypoxia. They can promote inflammation or suppress it, depending on what "awakened" them. For example, HIF-1 proteins ...

Studies have shown that the factors that promote the healing of diabetic foot ulcer are related to inhibiting apoptosis, promoting fibrocyte proliferation, promoting angiogenesis, accelerating ...

Thus, the elucidation of TAM–tumor cell interactions in animal models fits with the clinical observation of poor outcomes in breast cancers with central necrosis. [53] Those tumors with necrosis ...

Inflammatory processes are the body’s defence against local damage and disease. Inflammation involves the influx into organs of immune cells (white blood cells) from the blood. These cells deal with ...

In the present study, researchers used HFD-fed mice to investigate the exact mechanisms by which chronic IF exerts neuroprotective effects over LCN2 and GAL3-mediated neuroinflammation and adipose ...

Research interests Our research is focused mainly on the role of inflammatory cells called macrophages in tumour progression and responses to conventional anti-cancer treatments like chemotherapy and ...

When they detect a threat, myeloid cells called monocytes can transform into inflammatory macrophages -- attack cells that deal with intruders. Targeting HIF-2α: A New Therapeutic Strategy Dr.

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Corrigendum to "Bu Shen Yi Sui capsule promotes remyelination correlating with Sema3A/ NRP-1, LIF/LIFR and ... LPS-induced inflammation by shifting macrophages polarization through FAK/PI3K ...

HIF has a Low complaints rating. When we score policies we give each fund a complaints ... In the Northern Territory this fund has... 1 private hospital agreement out of an industry maximum of 1. 2 ...