USP25 does this by preventing HIF-1a from being ‘binned’, so it can form new blood vessels to supply the ... The Institute of Cancer Research (ICR) launched its new Centre for Protein Degradation last ...

The team's findings, published in the journal Water Biology and Security, revealed a novel function for usp3 in influencing hypoxia signaling and showed that tusp3-mediated HIF-1α degradation ...

More than a third of 50 recently surveyed Nobel laureates cited “population rise / environmental degradation” as the biggest threat to humankind. Second on the list was “nuclear war ...

For example, a two-computer complex employing graceful degradation would be reduced to using one system if the other fails. With fault tolerance, a third computer would be standing by to take over ...

Retraction Note: M2 macrophage-derived extracellular vesicles promote gastric cancer progression via a microRNA-130b-3p/MLL3/GRHL2 signaling cascade. Retraction Note ...

The rumen microbiota—a symbiont to its host and consists of critical functional substances—plays a vital role in the animal ...

One of our current projects, models the human Von Hippel Lindau disease, caused by mutation of the VHL gene. VHL is a negative regulator of the Hypoxia Inducible Factor (HIF) signalling pathway, which ...

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The EB-1A visa category is a critical pathway for attracting skilled individuals to fuel America's innovation engine. Right now, I believe we stand on the brink of a data-driven revolution that ...

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