and resident Kupffer cells (blue) and from injured hepatocytes (green). Oxidative stress, cytokine release, endotoxin, and ethanol and its metabolites can stimulate paracrine chemokine secretion ...

Through a unique fabrication technique, "islands" of human hepatocytes are cultured alongside stromal and Kupffer cells in a precise ratio. This setup replicates the liver's physiological ...

On the contrary, there is minimal expression of class I HLA antigens on hepatocytes, which favors decreased antigenicity. It is also thought that donor Kupffer cells may be replaced with host ...

The liver is largely comprised of hepatocytes, but Kupffer cells, endothelial cells and hepatic stellate cells are also present. Long-term machine perfusion holds great promise in the field of ...