As a result, this protein can bind to HIF1β and facilitate gene transcription of many HIF target genes (Figure 1; Schofield & Ratcliffe, 2004). Some organisms, like the roundworm C. elegans ...

The cells died in the most dangerous versions. The researchers discovered that the defective VHL gene elevated the activity of the HIF gene. While an excess of HIF protein can result in tumors ...

Sep. 25, 2024 — Adults with hemophilia B saw their number of bleeding episodes drop by an average of 71 percent after a single infusion of gene therapy, according to the new results of an ...

Mutations in the responsible gene rob cells of a normal version of ... unlike normal cells, cannot destroy HIF when oxygen is present. Both Kaelin and Ratcliffe then showed that the binding ...

Sep. 16, 2024 — CREME is a virtual laboratory that allows scientists to simulate specific decreases in gene activity. It offers a powerful new tool for identifying and understanding important ...

Nine companies joined The Crunchbase Unicorn Board in September, taking the board to just shy of 1,550 companies and $5.2 ...

The rumen microbiota—a symbiont to its host and consists of critical functional substances—plays a vital role in the animal ...

Current scientific techniques are not yet safe or effective enough to be used to create gene-edited babies, an international committee says. The technology could one day prevent parents from ...

Gene Park is a reporter for The Washington Post, covering video games and gaming culture. He joined The Post in 2015 as audience editor, and is a former reporter in the West Coast and Pacific region.

Checked for accuracy by our qualified fact-checkers, verifiers and subject experts. Find out more about fact-checking at CHOICE. HIF has a Low complaints rating. When we score policies we give each ...