Daprodustat is vying to become the first drug in the HIF-PHI inhibitor class to reach the US market, after the FDA rejected two others – FibroGen/AstraZeneca's roxadustat and Akebia's vadadustat ...

The start of the review sets up an FDA decision by 1 February next year and – if positive – could give GSK first-to-market advantage in the HIF-PHI class after two competing agents were turned ...

明确贫血的原因至关重要。肾性贫血的病理机制较为复杂，涵盖促红细胞生成素（EPO）生成不足及活性降低、铁缺乏及代谢障碍、营养不良、甲状旁腺功能亢进、炎症状态、尿毒症毒素、失血等方面。需明确是否存在肾性贫血之外的贫血性疾病，诸如营养不良性贫血、溶血性贫血 ...

All patients achieved the target hemoglobin level above 10 g/dl during the 24 weeks of combined therapy with ESA and HIF–PHI, which was maintained until the end of the follow-up period. This was ...

Many influential people in American history distinguished themselves academically during college when they were elected and inducted into the Phi Beta Kappa Society, a national academic honor ...

The Indian Council of Medical Research (ICMR) on Monday announced a partnership with domestic pharma giant Zydus Lifesciences ...

化疗相关性贫血（CIA）为肿瘤患者常见的不良反应，发生率与肿瘤类型、治疗方案及化疗周期等因素相关，可导致化疗药物剂量减少、化疗时间延迟等，无法保障患者化疗效果，从而影响生存时间。当前，CIA主要治疗方式包括输注红细胞、促红细胞生成治疗及补充铁剂等，但存在血源紧张、红细胞生成刺激剂和铁剂使用不规范、不良反应多等多种局限，亟需高效、安全且便捷的治疗方案以满足当下临床治疗需求。 2024年9月27日，在 ...

The ICMR has formalized a Memorandum of Agreement (MoA) with Zydus for a Phase IIa double-blind, randomized, ...

Founded on December 5, 1776, The Phi Beta Kappa Society is the nation’s oldest, largest and most prestigious academic honor society. It has chapters at 286 colleges and universities in the United ...

Find out more about fact-checking at CHOICE. HIF has a Low complaints rating. When we score policies we give each fund a complaints rating, based on the number of complaints and serious disputes the ...

(December 2018). Mouth breather? Enduring patterns of hypocapnia induce cerebral hypoxia and consequential cognitive impairments mediated by aberrant HIF-1 survival signals common to the cell danger ...