Citation: In silico model of rat hippocampal CA1 region integrates diverse experimental data from synapse to network (2024, November 5) retrieved 27 November 2024 from https://medicalxpress.com ...

Researchers have developed the most detailed 3D computational models of key brain regions, including the hippocampus and ...

A new study reveals how interneurons, brain cells that regulate the firing of other neurons, act as traffic controllers in ...

The plasticity of synaptic connections is critical to the functioning of local circuits as it is thought to underlie information processing and storage in the brain. Traditionally, synaptic plasticity ...

NMDA receptors are involved in LTP in many brain regions, especially the hippocampal CA1 region. For effective LTP, calcium influx through the NMDA receptor is necessary. Calcium that enters the ...

The hippocampus is one of the most fascinating ... a fourth paper in PLOS Biology presents a comprehensive in silico model of the rat CA1 region, integrating diverse experimental data from synapse ...