These results demonstrate that the expression of two RE1-containing genes is enhanced in C6 glioma cells by a histone deacetylase inhibitor ... of maximium power for 10 s on ice, repeated 4 ...
Drugs aimed at histone modifications are called histone deacetylase (HDAC) inhibitors. HDACs are enzymes that remove the acetyl groups from DNA, which condenses chromatin and stops transcription.