Researchers at Karolinska Institutet have mapped how small RNA molecules, such as the recently Nobel Prize-awarded microRNAs, ...

A recent study highlights how transposons, especially LINE-1, play a critical role in human embryo development.

In a paper published in SCIENCE CHINA Life Sciences, a team from Peking University Third Hospital delves into the sex ...

Transposons, once thought to be harmful, are crucial in early human development. They ensure embryo cells grow correctly.

Transposons, specifically LINE-1 elements, previously regarded as genomic parasites, play a pivotal role in early human ...

Results suggest novel roles for LINE1 transposable elements that can be explored in the contexts of diseases, from ...

传统方法仅使用胚胎内少量部分细胞进行遗传分析，不能代表整体胚胎的真实染色体组成。为全面解析人类早期胚胎的嵌合特征，研究首先收集了来源于志愿者捐赠的20枚囊胚期胚胎，分离每个胚胎的全部细胞并进行单细胞基因组测序，检测每个细胞的染色体核型。结果发现所有囊胚中均包含染色体异常细胞，为嵌合胚胎。此外，在20个囊胚中，有70%的囊胚存在染色体错误互补的细胞，提示染色体非整倍体来源于胚胎细胞有丝分裂产生的错误 ...

Their study, published in the journal Developmental Cell, indicates that transposable elements are critical to ensure that ...

Their study, published in the journal Developmental Cell, indicates that transposable elements are critical to ensure that human embryonic cells progress normally through early development, rather ...

When early cartographers undertook perilous expeditions to map unknown corners of the world with sextants, compasses, and ...