such as talin and α-actinin. The detailed sequence of events following ECM binding to the integrin is not known, but the β-subunit cytoplasmic domain interacts directly with talin, and talin ...

Figure 1: α v β 3 as a mediator of antiangiogenic regulators. Figure 2: Trans-dominant inhibition of proangiogenic integrins. In presenting these models for negative regulation by α v integrins ...