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腾讯网
17 天
γ-干扰素释放试验的结果解读:从固定阈值到边界范围的灵活应用
随着结核分枝杆菌感染的全球流行,准确的检测方法变得尤为重要。γ-干扰素释放试验(interferon-γreleaseassay,IGRA)是现代医学中用于检测结核分枝杆菌感染的主要工具之一,因其高特异性且不受卡介苗(BCG)接种影响,已在全球范围内广泛应用。 目前,常用的IGRA方法包括Quantiferon-TBGold(QFT)和T-SPOT.TB。本文将重点讨论QFT的检测原理、结果类型以 ...
Nature
5 年
Elevated IFN-γ can indirectly cause bone loss in osteoporosis
For example, activated T helper type 1 lymphocytes secrete interferon (IFN)-γ, which has potent effects on osteoclastogenesis in vivo and in vitro. IFN-γ, however, is known to cause both bone ...
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