综上所述,该研究发现蔗糖在一定条件下能够减轻DEN诱导的肝纤维化和肿瘤形成,并改善肝脏脂质代谢,表明蔗糖通过调控脂质代谢和氧化应激反应,对肝细胞癌的发展具有潜在的保护作用。
摘要: 癌细胞对化疗药物的耐药性大大降低了癌症患者的治疗效果,化疗引起的毒副作用也严重影响了患者的生活质量。茶中主要活性成分表没食子儿茶素-3-没食子酸酯(EGCG)与顺铂、5-FU、多柔比星和紫杉醇的联合使用,增强了它们对肿瘤的增敏效果,并对抗了癌细胞的耐药性。这些效应似乎通过多种机制介导,包括对抗癌症干细胞介导的药物耐药性、增强药物敏感性、诱导细胞周期停滞和凋亡,以及阻断血管生成。此外,EGC ...
该过程与氧化损伤密切相关,而“胞质接头蛋白Keap1-转录因子Nrf2-抗氧化反应元件Are”通路是人体最重要的抗氧化系统之一,其中转录因子Nrf2主要 ...
In human studies, Nrf2 suppression has been linked to cataract formation in lenses collected from diabetic and older patients ...
(C) Effects of 6-OHDA and sesaminol on nuclear translocation of Nrf2. SH-SY5Y cells were incubated with 1 μg/ml of sesaminol for 2 h, followed by treatment with 20 μM 6-OHDA for 3 h ...
ROME, Oct. 21, 2024 (GLOBE NEWSWIRE) — Angelini Pharma, part of the privately owned Angelini Industries, and Cureverse Inc., an early-stage research and development company, announced today that they ...
In human studies, Nrf2 suppression has been linked to cataract formation in lenses collected from diabetic and older patients, with the upregulation of Keap1 (an Nrf2 suppressor) found in these ...
Retraction Note: M2 macrophage-derived extracellular vesicles promote gastric cancer progression via a microRNA-130b-3p/MLL3/GRHL2 signaling cascade. Retraction Note ...
So, what's with the biscuits? Oh a triangulator machine! Very cool! Right, there are four different types of triangle. First, here's an isosceles triangle, it has two equal length sides and two ...
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