Researchers from the University of Illinois have discovered a key factor responsible for facilitating signal transduction in Cys-loop receptors, providing insight into a longstanding question in the ...

Finally, the SSRI-induced increase in serotonin concentration potentially impacts numerous serotonin receptor subtypes ... Cite this: Targeting Ligand-gated Ion Channels in Neurology and ...

The results are summarized in the form of 1) receptor-centric maps that illustrate ... Cite this: Targeting Ligand-gated Ion Channels in Neurology and Psychiatry: Is Pharmacological Promiscuity ...

Thus far, one antibody (BIL010t; Biosceptre) that targets a nonfunctional form of the ligand-gated ion channel P2X purinoceptor ... GPCRs [G protein-coupled receptors], which have large portions ...

Ion channels are integral membrane ... states to control the influx of Mg 2+ using an auto-ligand-gating regulation mechanism. Kainate receptors (KARs) contribute to excitatory neurotransmission ...

N-methyl D-aspartate (NMDA) receptors are ligand-gated cation channels activated by glutamate, an excitatory neurotransmitter. These receptors are located mostly at excitatory synapses and ...