DC-9476 has broad activity including decreasing macrophage activation, Th17 differentiation, IgG, and pro-inflammatory cytokines such as TNFα, IL-6, IL-17A and IL-17F. DC-9476 is expected to be ...
TH17-cells are believed to be involved in the ... Target identification in B and T cell deficiency, macrophage defects and hematopoiesis. • A tool for investigating IRF8 mediated issues ...