More importantly, they identified specific macrophage subpopulations that are critical for resolving MASH and liver fibrosis ...

Researchers developed novel genetic tools to trace, ablate, and manipulate p16^Ink4a+^ senescent cells, revealing their ...

More importantly, they identified specific macrophage subpopulations that are critical for resolving MASH and liver fibrosis ...

The findings are significant for the liver research community and others interested in the gut-liver axis. (A) AOAH cleaves the two piggyback fatty acyl chains from the lipid A moiety, inactivating ...

Liver fibrosis is the formation of tissue scars in the liver due to chronic inflammation and injury. Over time, fibrosis can impair liver function and may lead to cirrhosis or even liver cancer .

Identifying a New Liver Defender: The Role of Resident Macrophages Apr. 25, 2024 — Researchers discovered liver resident macrophages' pivotal role in defending against gut bacteria and related ...

Liver fibrosis is the formation of tissue scars in the liver due to chronic inflammation and injury. Over time, fibrosis can impair liver function and may lead to cirrhosis or even liver cancer.

These cells deal with microbes and repair tissue damage. Two main sub-types of immune cells are T cells and macrophages. T cells are designed to recognise the molecular signatures of particular ...

Fibrosis refers to aberrant ... using human hepatic stellate cells and macrophages from humans and mice in vitro, as well as mouse models of liver, kidney, and lung fibrosis," Pan continued.