Researchers from the University of Illinois have discovered a key factor responsible for facilitating signal transduction in Cys-loop receptors, providing insight into a longstanding question in the ...

Thus far, one antibody (BIL010t; Biosceptre) that targets a nonfunctional form of the ligand-gated ion channel P2X purinoceptor 7 has reached clinical trials for the treatment of basal cell carcinoma.

Cite this: Targeting Ligand-gated Ion Channels in Neurology and Psychiatry: Is Pharmacological Promiscuity an Obstacle or an Opportunity? - Medscape - Mar 02, 2010.