Drugs that target the proinflammatory mediator IL-1, for instance, can counteract disease in certain types of inflammatory conditions. But such drugs do not work well for other conditions ...

Histamine plays an important role in healthy immune functioning and neurotransmitter signaling. However, when these naturally ...

The researchers discovered that after a heart attack, monocytes migrate from the blood to the brain and produce a molecule ...

Maintaining the right balance of anti-inflammatory mediators, which allow tissue repair and healing, and pro-inflammatory mediators, to clear cellular debris and aggregated misfolded proteins ...

it is unclear whether chronic pollutant exposures are associated with endotoxin stimulated inflammatory mediators. Objectives: We examined associations between chronic exposures to outdoor air ...

Tumour Necrosis Factor TNF is crucial for defence but can drive chronic inflammation linked to arthritis and autoimmune diseases when overproduced ...

A handful of prunes a day protects older women against osteoporosis, according to research. Levels of bone-boosting hormone ...

Mediators of anaphylactic reactions:- Aside from mast cell tryptase, which other chemical inflammatory mediators offer potential as indicators of anaphylaxis? Why this is important:- Although mast ...

Periodontal disease triggers a cascade of inflammatory reactions, leading to the production of several inflammatory mediators ...

Research uncovers the impact of the airway microbiome on severe asthma, particularly neutrophilic asthma, linking specific ...

In AKI, immune cells known as macrophages produce lipid mediators (LMs), which are lipids with significant physiological activity and play a pivotal role in promoting and suppressing inflammation.

Leptomeningeal inflammation in a mouse model of multiple sclerosis triggers deeply penetrating gene changes in underlying brain tissue, described using spatial transcriptomics.